From what it sounds like it might be viral issues like Fish Pox, Lymphocystis, Columnaris. I'd suggest taking a photo of the infected fish and posting it or taking a look on google to see which issue it might be. Most cases are going to expect you to text your water PH, Nitrites, Nitrates etc and do a partial water change some even mention to take out your gravel and clean it also.
Sorry i couldn't really give you a straight answer other than it doesn't sound like Ich. Also make sure that you know what you are dealing with before you treat your tank, Loaches are sensitive to certain chemicals.
Happy fish keeping!
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