OK.... my 2c:
Firstly, I would not ever treat loaches with Copper-containing medications, not half-dose, not 1% dose. The specs for mycopur say
100 ml of
sera mycopur
contain:
acriflavine 210 mg
cupric chloride 11.8 mg
cupric sulfate 71.9 mg
aqua purificata ad 100 ml
http://www.akvaryumculuk.biz/sera_mycopur.pdf
All loaches are sensitive to copper, there are at least two mechanisms of how copper harms them, and making exact predictions is not possible -- some species are considerably more sensitive than others, and pH is a factor.
So, if anything, Diana's plan B.
But let's go to the beginning for a moment: just what are you treating? Just what is "fungus disease?"
Is this flex (columnaris) per chance? Then you can use a medication that does not contain copper... kanamycin or furan2 would usually work... just watch the cycle. If antibiotics are not available on your end, acriflavine alone tends to work, and it is safe to fish (not to the biofilter!)
or is this true fungus? Uncommon, but happens.... this is considerably trickier to cure, but still copper is not needed.