250 mg Capsules of Water Soluble Levamisol, NaCl, Piperazine, Magnesium Sulfate and Neomycin Sulfate Activity. When treating tanks I used 2 capsules Per 10g. Worked great in conjunction with Kanacyn to treat clowns with skinny...
Directions called for soaking food in it. I emptied the capsules into a cup, dissolved it in hot water, let it cool and poured it directly into the tank through a coffee filter.
Didn't kill any fish, plants, snails, or biofilters. Maybe I was just lucky? Dunno. Worked, though...
This one is from the Belle Island Aquarium-
Levamisole (13.65% injectable) - 2 ppm (1.1 ml per 20 gallons)
This medication chart suggests-
2 mg/L for 24 hours ONCE. Most effective against larval nematodes, swimbladder worms. no increase in effectiveness with higher dose.
In the book, Fish Disease: Diagnosis and Treatment by Edward Noga pg 288 (you can login to amazon.com and search inside this book, search "levamisole" or "288")-
The dosage they give here is 10mg/liter or 38mg/gallon of water for Anguillicola (nematode that lives in the swimbladder of eels) and other suspectible nonencyted nematodes. No mention of treatment time.
So far from what I've collected-
1mg/l (38mg/10g) 1 to 2 days for skin and gill flukes
2mg/l (76mg/10g) once per week for 3 weeks for Camallanus Nematodes
10mg/l (380mg/10g) for Anguillicola.
I have also asked a guy that i met at anoher site--a fella that teaches veterinary medicine--about dosing. waiting for his reply as well.
the requests ask if there is a relationship to body mass/size and amount of the compound.
Part of the dosing level confusion probably comes from teh same issue most of us were confused about--Levamisole base and Levamisole Hydrochloride. As martin mentioned, and DrMomFish--the trials were done by an individual. and, as we all know--results may vary.
I have used the protocol defined by DrMomFish many times and have never had a toxicity issue. That is why i am more patient waiting for replies than i am on most issues--lol.
good stuff keith!
I've read that one you've posted chefkeith, found it when I was going crazy and see no mention of 'hydrochloride'. This paper is actually one of those which had me nuts over whether or not it broke down at low pH.
I see no mention of which form of levamisole he's discussing and I think if it were levamisole hydrochloride he would have said so...I hope.One effective bath treatment dose is 2 ppm (mg/liter) levamisole for 24 hours, with a repeat treatment in two to three weeks.
In any case I'm waiting in hopes sully will hear back.
This is correct, but it does not follow that the base and Hcl are equally efficient. In fact, for the immune system modulation they do not seem to be:Graeme Robson wrote: The only important molecule is the levamisol not the others.
SourceFifty-nine (59) mg of levamisole HCl is equivalent to 50 mg of levamisole base.
While the difference is only 20%, it may be larger for other type of use.
Glad that the EDIS publications are helpful, but I do encourage you and
the other hobbyists to work with fish veterinarians as much as possible,
and ideally, have infections checked pre-and post-treatment (this can
often be done with fecal exams, if you are dealing with an intestinal
In answer to your question, the dosage rate for levamisole in a bath is
2 mg/L (2 ppm) for 24 hours (followed by 70-100% water change, and
siphon the bottoms of the tanks), with repeat treatments
necessary--retreat in 2-3 weeks, and probably one more time after that.
This is regardless of size of fish.
Hope this helps.
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